Bioinformatics and the theoretical foundations of molecular biology

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Bioinformatics and the theoretical foundations of molecular biology

To continue on some issues raised previously (Ouzounis, 2000), I would like to examine the principal elements of bioinformatics and its relationship to biological sciences. In various social settings, over conference dinners, at annual retreats and other occasions, I have been involved in these types of casual debates. Is bioinformatics a science or a mere technology platform? Or, put more blun...

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Affiliations: ∗ Theoretical Biology and Bioinformatics Group, Utrecht University Corresponding author:

Eukaryotes appear to evolve by micro and macro rearrangements. This is observed not only for long-term evolutionary adaptation, but also in short-term experimental evolution of yeast, S. cerevisiae. Moreover, based on these and other experiments it has been postulated that repeat elements, retroposons for example, mediate such events. We study an evolutionary model in which genomes with retropo...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2002

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/18.3.377